Cargando…

The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states

Heterochromatin formation requires three distinct steps: nucleation, self-propagation (spreading) along the chromosome, and faithful maintenance after each replication cycle. Impeding any of those steps induces heterochromatin defects and improper gene expression. The essential histone chaperone FAC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Murawska, Magdalena, Greenstein, R.A., Schauer, Tamas, Olsen, Karl C.F., Ng, Henry, Ladurner, Andreas G., Al-Sady, Bassem, Braun, Sigurd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608617/ https://www.ncbi.nlm.nih.gov/pubmed/34731638 http://dx.doi.org/10.1016/j.celrep.2021.109944

Ejemplares similares

Local chromatin context regulates the genetic requirements of the heterochromatin spreading reaction
por: Greenstein, R. A., et al.
Publicado: (2022)

Set1/COMPASS repels heterochromatin invasion at euchromatic sites by disrupting Suv39/Clr4 activity and nucleosome stability
por: Greenstein, R.A., et al.
Publicado: (2020)

A role for the histone chaperone DAXX in the structural organization of heterochromatin
por: Rapkin, Lindsy M, et al.
Publicado: (2013)

The histone chaperone DAXX maintains the structural organization of heterochromatin domains
por: Rapkin, Lindsy M., et al.
Publicado: (2015)

Regulation of the heterochromatin spreading reaction by trans-acting factors
por: Hamali, Bulut, et al.
Publicado: (2023)

HDAC mediated suppression of histone turnover promotes epigenetic stability of heterochromatin
por: Aygün, Ozan, et al.
Publicado: (2013)

Noncoding RNA-nucleated heterochromatin spreading is intrinsically labile and requires accessory elements for epigenetic stability
por: Greenstein, R A, et al.
Publicado: (2018)

The histone chaperone FACT modulates nucleosome structure by tethering its components
por: Wang, Tao, et al.
Publicado: (2018)

Prognostic value of histone chaperone FACT subunits expression in breast cancer
por: Attwood, Kristopher, et al.
Publicado: (2017)

The CENP-T/-W complex is a binding partner of the histone chaperone FACT
por: Prendergast, Lisa, et al.
Publicado: (2016)

Histone chaperone FACT is essential to overcome replication stress in mammalian cells
por: Prendergast, Laura, et al.
Publicado: (2020)

Histone chaperone Spt16p is required for heterochromatin mediated silencing in budding yeast
por: Yan, Xiaowei, et al.
Publicado: (2017)

New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone
por: Voon, Hsiao P.J., et al.
Publicado: (2016)

Intrinsic Toxicity of Unchecked Heterochromatin Spread Is Suppressed by Redundant Chromatin Boundary Functions in Schizosacchromyces pombe
por: Garcia, Jennifer F., et al.
Publicado: (2015)

Structure of the human histone chaperone FACT Spt16 N-terminal domain
por: Marcianò, G., et al.
Publicado: (2016)

Histone chaperone FACT represses retrotransposon MERVL and MERVL-derived cryptic promoters
por: Chen, Fuquan, et al.
Publicado: (2020)

A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading
por: Shan, Chun-Min, et al.
Publicado: (2016)

Histone Chaperone FACT Coordinates Nucleosome Interaction through Multiple Synergistic Binding Events
por: Winkler, Duane D., et al.
Publicado: (2011)

Histone Chaperones Spt6 and FACT: Similarities and Differences in Modes of Action at Transcribed Genes
por: Duina, Andrea A.
Publicado: (2011)

Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV-1 integration
por: Matysiak, Julien, et al.
Publicado: (2017)

Essential histone chaperones collaborate to regulate transcription and chromatin integrity
por: Viktorovskaya, Olga, et al.
Publicado: (2021)

Global regulation of heterochromatin spreading by Leo1
por: Verrier, Laure, et al.
Publicado: (2015)

H2B ubiquitylation and the histone chaperone Asf1 cooperatively mediate the formation and maintenance of heterochromatin silencing
por: Wu, Meng-Ying, et al.
Publicado: (2017)

A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading
por: Challal, Drice, et al.
Publicado: (2023)

The FACT Histone Chaperone: Tuning Gene Transcription in the Chromatin Context to Modulate Plant Growth and Development
por: Grasser, Klaus D.
Publicado: (2020)

The euchromatic histone mark H3K36me3 preserves heterochromatin through sequestration of an acetyltransferase complex in fission yeast
por: Georgescu, Paula R., et al.
Publicado: (2020)

Histone chaperone regulates replication
por: Robinson, Richard
Publicado: (2008)

Histone acetylation-independent transcription stimulation by a histone chaperone
por: Kato, Kohsuke, et al.
Publicado: (2007)

Nucleosome proteostasis and histone turnover
por: Arrieta, Adrian, et al.
Publicado: (2022)

Histone deacetylation promotes transcriptional silencing at facultative heterochromatin
por: Watts, Beth R, et al.
Publicado: (2018)

Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility
por: Laurentino, Eliane C, et al.
Publicado: (2011)

The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage
por: Piquet, Sandra, et al.
Publicado: (2018)

The histone chaperone sNASP binds a conserved peptide motif within the globular core of histone H3 through its TPR repeats
por: Bowman, Andrew, et al.
Publicado: (2016)

Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci
por: Kennedy, Alyssa L, et al.
Publicado: (2010)

Histone Chaperones as Cardinal Players in Development
por: Rajam, Sruthy Manuraj, et al.
Publicado: (2022)

Histone Variants and Their Chaperones in Hematological Malignancies
por: Kirkiz, Ecem, et al.
Publicado: (2023)

Methylation of histone H3 at lysine 23 in meiotic heterochromatin
por: Papazvan, Romeo, et al.
Publicado: (2013)

Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release
por: Warren, Christopher, et al.
Publicado: (2017)

A potential histone-chaperone activity for the MIER1 histone deacetylase complex
por: Wang, Siyu, et al.
Publicado: (2023)

Sensitive and Quantitative Three-Color Protein Imaging in Fission Yeast Using Spectrally Diverse, Recoded Fluorescent Proteins with Experimentally-Characterized In Vivo Maturation Kinetics
por: Al-Sady, Bassem, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_7sjdoqnhd812gfum0rsf6nml4h