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Protocol for scChaRM-seq: Simultaneous profiling of gene expression, DNA methylation, and chromatin accessibility in single cells

Single-cell multi-omics sequencing technology can infer cell heterogeneity and reveal relationships across molecular layers. Combining single-cell RNA sequencing, DNA methylation, and chromatin accessibility allows a multimodal understanding of cell function and epigenetic regulation within individu...

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Detalles Bibliográficos
Autores principales: Yan, Rui, Cheng, Xin, Guo, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608654/
https://www.ncbi.nlm.nih.gov/pubmed/34849489
http://dx.doi.org/10.1016/j.xpro.2021.100972