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Integrating genome-wide association and transcriptome prediction model identifies novel target genes for osteoporosis

SUMMARY: In this study, we integrated large-scale GWAS summary data and used the predicted transcriptome-wide association study method to discover novel genes associated with osteoporosis. We identified 204 candidate genes, which provide novel clues for understanding the genetic mechanism of osteopo...

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Detalles Bibliográficos
Autores principales: Zhu, M., Yin, P., Hu, F., Jiang, J., Yin, L., Li, Y., Wang, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608767/
https://www.ncbi.nlm.nih.gov/pubmed/34142171
http://dx.doi.org/10.1007/s00198-021-06024-z