Polymorphic variants of alkaline phosphatase gene correlate with clinical signs of adult hypophosphatasia?

SUMMARY: We analyzed polymorphism of the ALPL gene in patients with low serum levels of tissue-nonspecific alkaline phosphatase (TNAP). The presence of three or more of the less frequent alleles of ALPL polymorphisms was associated with significantly lower TNAP serum level and higher frequencies of...

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Detalles Bibliográficos
Autores principales: Masi, L., Marini, F., Franceschelli, F., Leoncini, G., Cianferotti, L., Cioppi, F., Giusti, F., Marcucci, G., Gronchi, G., Brandi, M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608776/
https://www.ncbi.nlm.nih.gov/pubmed/34097127
http://dx.doi.org/10.1007/s00198-021-05893-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608776/
https://www.ncbi.nlm.nih.gov/pubmed/34097127
http://dx.doi.org/10.1007/s00198-021-05893-8

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