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Virus-based vaccine vectors with distinct replication mechanisms differentially infect and activate dendritic cells
The precise mechanism by which many virus-based vectors activate immune responses remains unknown. Dendritic cells (DCs) play key roles in priming T cell responses and controlling virus replication, but their functions in generating protective immunity following vaccination with viral vectors are no...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608815/ https://www.ncbi.nlm.nih.gov/pubmed/34811393 http://dx.doi.org/10.1038/s41541-021-00400-w |