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Virus-based vaccine vectors with distinct replication mechanisms differentially infect and activate dendritic cells

The precise mechanism by which many virus-based vectors activate immune responses remains unknown. Dendritic cells (DCs) play key roles in priming T cell responses and controlling virus replication, but their functions in generating protective immunity following vaccination with viral vectors are no...

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Detalles Bibliográficos
Autores principales: Chiale, Carolina, Marchese, Anthony M., Furuya, Yoichi, Robek, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608815/
https://www.ncbi.nlm.nih.gov/pubmed/34811393
http://dx.doi.org/10.1038/s41541-021-00400-w