Bak instead of Bax plays a key role in metformin-induced apoptosis s in HCT116 cells

Metformin (Met) exhibits anticancer ability in various cancer cell lines. This report aims to explore the exact molecular mechanism of Met-induced apoptosis in HCT116 cells, a human colorectal cancer cell line. Met-induced reactive oxygen species (ROS) increase and ROS-dependent cell death accompani...

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Detalles Bibliográficos
Autores principales: Chen, Hongce, Sun, Beini, Sun, Han, Xu, Lingjun, Wu, Guihao, Tu, Zhuang, Cheng, Xuecheng, Fan, Xuhong, Mai, Zihao, Tang, Qiling, Wang, Xiaoping, Chen, Tongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608863/
https://www.ncbi.nlm.nih.gov/pubmed/34811352
http://dx.doi.org/10.1038/s41420-021-00755-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608863/
https://www.ncbi.nlm.nih.gov/pubmed/34811352
http://dx.doi.org/10.1038/s41420-021-00755-y

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