Identification of downstream effectors of retinoic acid specifying the zebrafish pancreas by integrative genomics

Retinoic acid (RA) is a key signal for the specification of the pancreas. Still, the gene regulatory cascade triggered by RA in the endoderm remains poorly characterized. In this study, we investigated this regulatory network in zebrafish by combining RNA-seq, RAR ChIP-seq and ATAC-seq assays. By an...

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Detalles Bibliográficos
Autores principales: López-Pérez, Ana R., Balwierz, Piotr J., Lenhard, Boris, Muller, Ferenc, Wardle, Fiona C., Manfroid, Isabelle, Voz, Marianne L., Peers, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608873/
https://www.ncbi.nlm.nih.gov/pubmed/34811400
http://dx.doi.org/10.1038/s41598-021-02039-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608873/
https://www.ncbi.nlm.nih.gov/pubmed/34811400
http://dx.doi.org/10.1038/s41598-021-02039-y

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