MUC1 ectodomain is a flagellin-targeting decoy receptor and biomarker operative during Pseudomonas aeruginosa lung infection

We previously reported that flagellin-expressing Pseudomonas aeruginosa (Pa) provokes NEU1 sialidase-mediated MUC1 ectodomain (MUC1-ED) desialylation and MUC1-ED shedding from murine lungs in vivo. Here, we asked whether Pa in the lungs of patients with ventilator-associated pneumonia might also inc...

Descripción completa

Detalles Bibliográficos
Autores principales: Verceles, Avelino C., Bhat, Pavan, Nagaria, Zain, Martin, Destiny, Patel, Harsh, Ntem-Mensah, Afua, Hyun, Sang W., Hahn, Andrea, Jeudy, Jean, Cross, Alan S., Lillehoj, Erik P., Goldblum, Simeon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608881/
https://www.ncbi.nlm.nih.gov/pubmed/34811449
http://dx.doi.org/10.1038/s41598-021-02242-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608881/
https://www.ncbi.nlm.nih.gov/pubmed/34811449
http://dx.doi.org/10.1038/s41598-021-02242-x

Ejemplares similares