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MUC1 ectodomain is a flagellin-targeting decoy receptor and biomarker operative during Pseudomonas aeruginosa lung infection

We previously reported that flagellin-expressing Pseudomonas aeruginosa (Pa) provokes NEU1 sialidase-mediated MUC1 ectodomain (MUC1-ED) desialylation and MUC1-ED shedding from murine lungs in vivo. Here, we asked whether Pa in the lungs of patients with ventilator-associated pneumonia might also inc...

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Detalles Bibliográficos
Autores principales:	Verceles, Avelino C., Bhat, Pavan, Nagaria, Zain, Martin, Destiny, Patel, Harsh, Ntem-Mensah, Afua, Hyun, Sang W., Hahn, Andrea, Jeudy, Jean, Cross, Alan S., Lillehoj, Erik P., Goldblum, Simeon E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608881/ https://www.ncbi.nlm.nih.gov/pubmed/34811449 http://dx.doi.org/10.1038/s41598-021-02242-x

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