Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs

Osteoclasts are multinucleated, bone-resorbing cells. However, they also digest cartilage during skeletal maintenance, development and in degradative conditions including osteoarthritis, rheumatoid arthritis and primary bone sarcoma. This study explores the mechanisms behind the osteoclast–cartilage...

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Detalles Bibliográficos
Autores principales: Larrouture, Quitterie C., Cribbs, Adam P., Rao, Srinivasa R., Philpott, Martin, Snelling, Sarah J., Knowles, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608887/
https://www.ncbi.nlm.nih.gov/pubmed/34811438
http://dx.doi.org/10.1038/s41598-021-02246-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608887/
https://www.ncbi.nlm.nih.gov/pubmed/34811438
http://dx.doi.org/10.1038/s41598-021-02246-7

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