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Advancement of pharmacokinetic models of iohexol in patients aged 70 years or older with impaired kidney function

Plasma clearance of iohexol is a pivotal metric to quantify glomerular filtration rate (GFR), but the optimal timing and frequency of plasma sampling remain to be assessed. In this study, we evaluated the impact of a Bayesian estimation procedure on iohexol clearance estimates, and we identified an...

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Detalles Bibliográficos
Autores principales: Taubert, Max, Schaeffner, Elke, Martus, Peter, van der Giet, Markus, Fuhr, Uwe, Lösment, Amina, Ebert, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608910/
https://www.ncbi.nlm.nih.gov/pubmed/34811403
http://dx.doi.org/10.1038/s41598-021-01892-1