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Evaluation of the effect of filtered ultrafine particulate matter on bleomycin-induced lung fibrosis in a rat model using computed tomography, histopathologic analysis, and RNA sequencing

We aimed to investigate the effect of chronic particulate matter (PM) exposure on bleomycin-induced lung fibrosis in a rat model using chest CT, histopathologic evaluation, and RNA-sequencing. A bleomycin solution was intratracheally administrated to 20 male rats. For chronic PM exposure, after four...

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Detalles Bibliográficos
Autores principales: Kim, Cherry, Jeong, Sang Hoon, Kim, Jaeyoung, Kang, Ja Young, Nam, Yoon Jeong, Togloom, Ariunaa, Cha, Jaehyung, Lee, Ki Yeol, Lee, Chang Hyun, Park, Eun-Kee, Lee, Ju-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609022/
https://www.ncbi.nlm.nih.gov/pubmed/34811439
http://dx.doi.org/10.1038/s41598-021-02140-2