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Dynamic changes in immune gene co-expression networks predict development of type 1 diabetes

Significant progress has been made in elucidating genetic risk factors influencing Type 1 diabetes (T1D); however, features other than genetic variants that initiate and/or accelerate islet autoimmunity that lead to the development of clinical T1D remain largely unknown. We hypothesized that genetic...

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Detalles Bibliográficos
Autores principales: Brænne, Ingrid, Onengut-Gumuscu, Suna, Chen, Ruoxi, Manichaikul, Ani W., Rich, Stephen S., Chen, Wei-Min, Farber, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609030/
https://www.ncbi.nlm.nih.gov/pubmed/34811390
http://dx.doi.org/10.1038/s41598-021-01840-z