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Deep-Learning-Derived Evaluation Metrics Enable Effective Benchmarking of Computational Tools for Phosphopeptide Identification

Tandem mass spectrometry (MS/MS)-based phosphoproteomics is a powerful technology for global phosphorylation analysis. However, applying four computational pipelines to a typical mass spectrometry (MS)-based phosphoproteomic dataset from a human cancer study, we observed a large discrepancy among th...

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Detalles Bibliográficos
Autores principales: Jiang, Wen, Wen, Bo, Li, Kai, Zeng, Wen-Feng, da Veiga Leprevost, Felipe, Moon, Jamie, Petyuk, Vladislav A., Edwards, Nathan J., Liu, Tao, Nesvizhskii, Alexey I., Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609164/
https://www.ncbi.nlm.nih.gov/pubmed/34737085
http://dx.doi.org/10.1016/j.mcpro.2021.100171