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An open-label, randomized, single intravenous dosing study to investigate the effect of fixed-dose combinations of tenofovir/lamivudine or atazanavir/ritonavir on the pharmacokinetics of remdesivir in Ugandan healthy volunteers (RemTLAR)

BACKGROUND: Remdesivir is a novel broad-spectrum antiviral therapeutic with activity against several viruses that cause emerging infectious diseases. The purpose of this study is to explore how commonly utilized antiretroviral therapy (tenofovir disoproxil fumarate/lamivudine [TDF/3TC] and atazanavi...

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Detalles Bibliográficos
Autores principales: Walimbwa, Stephen I., Kaboggoza, Julian P., Waitt, Catriona, Byakika-Kibwika, Pauline, D’Avolio, Antonio, Lamorde, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609173/
https://www.ncbi.nlm.nih.gov/pubmed/34814933
http://dx.doi.org/10.1186/s13063-021-05752-1