Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis

Fibrosis-driven solid organ failure is an enormous burden on global health. Spiny mice (Acomys) are terrestrial mammals that can regenerate severe skin wounds without scars to avoid predation. Whether spiny mice also regenerate internal organ injuries is unknown. Here, we show that despite equivalen...

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Detalles Bibliográficos
Autores principales: Okamura, Daryl M., Brewer, Chris M., Wakenight, Paul, Bahrami, Nadia, Bernardi, Kristina, Tran, Amy, Olson, Jill, Shi, Xiaogang, Yeh, Szu-Ying, Piliponsky, Adrian, Collins, Sarah J., Nguyen, Elizabeth D., Timms, Andrew E., MacDonald, James W., Bammler, Theo K., Nelson, Branden R., Millen, Kathleen J., Beier, David R., Majesky, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609232/
https://www.ncbi.nlm.nih.gov/pubmed/34849462
http://dx.doi.org/10.1016/j.isci.2021.103269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609232/
https://www.ncbi.nlm.nih.gov/pubmed/34849462
http://dx.doi.org/10.1016/j.isci.2021.103269

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