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Cognitive deficits and impaired hippocampal long-term potentiation in K(ATP)-induced DEND syndrome
ATP-sensitive potassium (K(ATP)) gain-of-function (GOF) mutations cause neonatal diabetes, with some individuals exhibiting developmental delay, epilepsy, and neonatal diabetes (DEND) syndrome. Mice expressing K(ATP)-GOF mutations pan-neuronally (nK(ATP)-GOF) demonstrated sensorimotor and cognitive...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609313/ https://www.ncbi.nlm.nih.gov/pubmed/34732576 http://dx.doi.org/10.1073/pnas.2109721118 |