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Cognitive deficits and impaired hippocampal long-term potentiation in K(ATP)-induced DEND syndrome

ATP-sensitive potassium (K(ATP)) gain-of-function (GOF) mutations cause neonatal diabetes, with some individuals exhibiting developmental delay, epilepsy, and neonatal diabetes (DEND) syndrome. Mice expressing K(ATP)-GOF mutations pan-neuronally (nK(ATP)-GOF) demonstrated sensorimotor and cognitive...

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Detalles Bibliográficos
Autores principales:	Yahil, Shaul, Wozniak, David F., Yan, Zihan, Mennerick, Steven, Remedi, Maria S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609313/ https://www.ncbi.nlm.nih.gov/pubmed/34732576 http://dx.doi.org/10.1073/pnas.2109721118

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