Cargando…

Direct imaging of intraflagellar-transport turnarounds reveals that motors detach, diffuse, and reattach to opposite-direction trains

Intraflagellar transport (IFT), a bidirectional intracellular transport mechanism in cilia, relies on the cooperation of kinesin-2 and IFT-dynein motors. In Caenorhabditis elegans chemosensory cilia, motors undergo rapid turnarounds to effectively work together in driving IFT. Here, we push the enve...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhiqing, Danné, Noémie, Meddens, Bonno, Heller, Iddo, Peterman, Erwin J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609318/
https://www.ncbi.nlm.nih.gov/pubmed/34732580
http://dx.doi.org/10.1073/pnas.2115089118