Herpes Simplex Virus Type 1 Infection Disturbs the Mitochondrial Network, Leading to Type I Interferon Production through the RNA Polymerase III/RIG-I Pathway

Viruses have evolved a plethora of mechanisms to impair host innate immune responses. Herpes simplex virus type 1 (HSV-1), a double-stranded linear DNA virus, impairs the mitochondrial network and dynamics predominantly through the UL12.5 gene. We demonstrated that HSV-1 infection induced a remodeli...

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Detalles Bibliográficos
Autores principales: Berry, Noémie, Suspène, Rodolphe, Caval, Vincent, Khalfi, Pierre, Beauclair, Guillaume, Rigaud, Stéphane, Blanc, Hervé, Vignuzzi, Marco, Wain-Hobson, Simon, Vartanian, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609356/
https://www.ncbi.nlm.nih.gov/pubmed/34809467
http://dx.doi.org/10.1128/mBio.02557-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609356/
https://www.ncbi.nlm.nih.gov/pubmed/34809467
http://dx.doi.org/10.1128/mBio.02557-21

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