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Influenza A Virus Defective Viral Genomes Are Inefficiently Packaged into Virions Relative to Wild-Type Genomic RNAs

Deletion-containing viral genomes (DelVGs) are commonly produced during influenza A virus infection and have been implicated in influencing clinical infection outcomes. Despite their ubiquity, the specific molecular mechanisms that govern DelVG formation and their packaging into defective interferin...

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Detalles Bibliográficos
Autores principales: Alnaji, Fadi G., Reiser, William K., Rivera-Cardona, Joel, te Velthuis, Aartjan J. W., Brooke, Christopher B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609359/
https://www.ncbi.nlm.nih.gov/pubmed/34809454
http://dx.doi.org/10.1128/mBio.02959-21