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Association between senescence of T cells and disease activity in patients with systemic lupus erythematosus

OBJECTIVES: Systemic lupus erythematosus (SLE) patients are predisposed to chronic immune activation, leading to accelerated immunosenescence. The aging of the immune system causes the T cells to express several senescence markers such as CD57 and KLRG1, which produce pro-inflammatory cytokine inter...

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Detalles Bibliográficos
Autores principales: Kalim, Handono, Wahono, Cesarius Singgih, Permana, Bunga Petriana Oktarini, Pratama, Mirza Zaka, Handono, Kusworini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609380/
https://www.ncbi.nlm.nih.gov/pubmed/34819703
http://dx.doi.org/10.5114/reum.2021.110318