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Glutathione peroxidase 4 regulated neutrophil ferroptosis induces systemic autoimmunity
The linkage between neutrophil death and the development of autoimmunity has not been thoroughly explored. Here, we show that neutrophils from either lupus-prone mice or patients with systemic lupus erythematosus (SLE) undergo ferroptosis. Mechanistically, autoantibodies and interferon-α present in...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609402/ https://www.ncbi.nlm.nih.gov/pubmed/34385713 http://dx.doi.org/10.1038/s41590-021-00993-3 |