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Very long O‐antigen chains of Salmonella Paratyphi A inhibit inflammasome activation and pyroptotic cell death

Salmonella Paratyphi A (SPtA) remains one of the leading causes of enteric (typhoid) fever. Yet, despite the recent increased rate of isolation from patients in Asia, our understanding of its pathogenesis is incomplete. Here we investigated inflammasome activation in human macrophages infected with...

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Detalles Bibliográficos
Autores principales: Mylona, Elli, Sanchez‐Garrido, Julia, Hoang Thu, Trang Nguyen, Dongol, Sabina, Karkey, Abhilasha, Baker, Stephen, Shenoy, Avinash R., Frankel, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609438/
https://www.ncbi.nlm.nih.gov/pubmed/33355403
http://dx.doi.org/10.1111/cmi.13306