Enhanced delivery efficiency and sustained release of biopharmaceuticals by complexation-based gel encapsulated coated microneedles: rhIFNα-1b example

Coated microneedles (MNs) are widely used for delivering biopharmaceuticals. In this study, a novel gel encapsulated coated MNs (GEC-MNs) was developed. The water-soluble drug coating was encapsulated with sodium alginate (SA) in situ complexation gel. The manufacturing process of GEC-MNs was optimi...

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Detalles Bibliográficos
Autores principales: Zhou, Zequan, Zhang, Suohui, Yang, Guozhong, Gao, Yunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2021
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609446/
https://www.ncbi.nlm.nih.gov/pubmed/34849166
http://dx.doi.org/10.1016/j.ajps.2021.05.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609446/
https://www.ncbi.nlm.nih.gov/pubmed/34849166
http://dx.doi.org/10.1016/j.ajps.2021.05.002

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