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Rapid Analysis of ADP-Ribosylation Dynamics and Site-Specificity Using TLC-MALDI

[Image: see text] Poly(ADP-ribose) polymerases, PARPs, transfer ADP-ribose onto target proteins from nicotinamide adenine dinucleotide (NAD(+)). Current mass spectrometric analytical methods require proteolysis of target proteins, limiting the study of dynamic ADP-ribosylation on contiguous proteins...

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Detalles Bibliográficos
Autores principales: Wallace, Sean R., Chihab, Leila Y., Yamasaki, Miles, Yoshinaga, Braden T., Torres, Yazmin M., Rideaux, Damon, Javed, Zeeshan, Turumella, Soumya, Zhang, Michelle, Lawton, Dylan R., Fuller, Amelia A., Carter-O’Connell, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609518/
https://www.ncbi.nlm.nih.gov/pubmed/34647721
http://dx.doi.org/10.1021/acschembio.1c00542