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Rapid Analysis of ADP-Ribosylation Dynamics and Site-Specificity Using TLC-MALDI
[Image: see text] Poly(ADP-ribose) polymerases, PARPs, transfer ADP-ribose onto target proteins from nicotinamide adenine dinucleotide (NAD(+)). Current mass spectrometric analytical methods require proteolysis of target proteins, limiting the study of dynamic ADP-ribosylation on contiguous proteins...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609518/ https://www.ncbi.nlm.nih.gov/pubmed/34647721 http://dx.doi.org/10.1021/acschembio.1c00542 |