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Potent Inhibitor of Human Trypsins from the Aeruginosin Family of Natural Products

[Image: see text] Serine proteases regulate many physiological processes and play a key role in a variety of cancers. Aeruginosins are a family of natural products produced by cyanobacteria that exhibit pronounced structural diversity and potent serine protease inhibition. Here, we sequenced the com...

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Detalles Bibliográficos
Autores principales: Ahmed, Muhammad N., Wahlsten, Matti, Jokela, Jouni, Nees, Matthias, Stenman, Ulf-Håkan, Alvarenga, Danillo O., Strandin, Tomas, Sivonen, Kaarina, Poso, Antti, Permi, Perttu, Metsä-Ketelä, Mikko, Koistinen, Hannu, Fewer, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609519/
https://www.ncbi.nlm.nih.gov/pubmed/34661384
http://dx.doi.org/10.1021/acschembio.1c00611