Cargando…
Potent Inhibitor of Human Trypsins from the Aeruginosin Family of Natural Products
[Image: see text] Serine proteases regulate many physiological processes and play a key role in a variety of cancers. Aeruginosins are a family of natural products produced by cyanobacteria that exhibit pronounced structural diversity and potent serine protease inhibition. Here, we sequenced the com...
Autores principales: | Ahmed, Muhammad N., Wahlsten, Matti, Jokela, Jouni, Nees, Matthias, Stenman, Ulf-Håkan, Alvarenga, Danillo O., Strandin, Tomas, Sivonen, Kaarina, Poso, Antti, Permi, Perttu, Metsä-Ketelä, Mikko, Koistinen, Hannu, Fewer, David P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609519/ https://www.ncbi.nlm.nih.gov/pubmed/34661384 http://dx.doi.org/10.1021/acschembio.1c00611 |
Ejemplares similares
-
New Structural Variants of Aeruginosin Produced by the Toxic Bloom Forming Cyanobacterium Nodularia spumigena
por: Fewer, David P., et al.
Publicado: (2013) -
The Biosynthesis of Rare Homo-Amino Acid Containing Variants of Microcystin by a Benthic Cyanobacterium
por: Shishido, Tânia Keiko, et al.
Publicado: (2019) -
Anabaenolysins, Novel Cytolytic Lipopeptides from Benthic Anabaena Cyanobacteria
por: Jokela, Jouni, et al.
Publicado: (2012) -
The Swinholide Biosynthesis Gene Cluster from a Terrestrial Cyanobacterium, Nostoc sp. Strain UHCC 0450
por: Humisto, Anu, et al.
Publicado: (2018) -
Production of High Amounts of Hepatotoxin Nodularin and New Protease Inhibitors Pseudospumigins by the Brazilian Benthic Nostoc sp. CENA543
por: Jokela, Jouni, et al.
Publicado: (2017)