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Transannular Enantioselective (3 + 2) Cycloaddition of Cycloalkenone Hydrazones under Brønsted Acid Catalysis

[Image: see text] Hydrazones derived from cycloalkenones undergo an enantioselective transannular formal (3 + 2) cycloaddition catalyzed by a chiral phosphoric acid. The reaction provides high yields and excellent stereocontrol in the formation of complex adducts with one or two α-tertiary amine moi...

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Detalles Bibliográficos
Autores principales: Sendra, Jana, Reyes, Efraim, Prieto, Liher, Fernández, Elena, Vicario, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609578/
https://www.ncbi.nlm.nih.gov/pubmed/34726408
http://dx.doi.org/10.1021/acs.orglett.1c03190