Regulation of neuronal excitation–transcription coupling by Kv2.1-induced clustering of somatic L-type Ca(2+) channels at ER-PM junctions

In mammalian brain neurons, membrane depolarization leads to voltage-gated Ca(2+) channel-mediated Ca(2+) influx that triggers diverse cellular responses, including gene expression, in a process termed excitation–transcription coupling. Neuronal L-type Ca(2+) channels, which have prominent populatio...

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Detalles Bibliográficos
Autores principales: Vierra, Nicholas C., O’Dwyer, Samantha C., Matsumoto, Collin, Santana, L. Fernando, Trimmer, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609631/
https://www.ncbi.nlm.nih.gov/pubmed/34750263
http://dx.doi.org/10.1073/pnas.2110094118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609631/
https://www.ncbi.nlm.nih.gov/pubmed/34750263
http://dx.doi.org/10.1073/pnas.2110094118

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