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Regulation of neuronal excitation–transcription coupling by Kv2.1-induced clustering of somatic L-type Ca(2+) channels at ER-PM junctions
In mammalian brain neurons, membrane depolarization leads to voltage-gated Ca(2+) channel-mediated Ca(2+) influx that triggers diverse cellular responses, including gene expression, in a process termed excitation–transcription coupling. Neuronal L-type Ca(2+) channels, which have prominent populatio...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609631/ https://www.ncbi.nlm.nih.gov/pubmed/34750263 http://dx.doi.org/10.1073/pnas.2110094118 |