DNAJB6b is Downregulated in Synucleinopathies

BACKGROUND: α-synuclein (α-syn) aggregation contributes to the progression of multiple neurodegenerative diseases. We recently found that the isoform b of the co-chaperone DNAJB6 is a strong suppressor of α-syn aggregation in vivo and in vitro. However, nothing is known about the role of the endogen...

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Detalles Bibliográficos
Autores principales: Folke, Jonas, Arkan, Sertan, Martinsson, Isak, Aznar, Susana, Gouras, Gunnar, Brudek, Tomasz, Hansen, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609689/
https://www.ncbi.nlm.nih.gov/pubmed/34334418
http://dx.doi.org/10.3233/JPD-202512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609689/
https://www.ncbi.nlm.nih.gov/pubmed/34334418
http://dx.doi.org/10.3233/JPD-202512

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