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DNAJB6b is Downregulated in Synucleinopathies
BACKGROUND: α-synuclein (α-syn) aggregation contributes to the progression of multiple neurodegenerative diseases. We recently found that the isoform b of the co-chaperone DNAJB6 is a strong suppressor of α-syn aggregation in vivo and in vitro. However, nothing is known about the role of the endogen...
Autores principales: | Folke, Jonas, Arkan, Sertan, Martinsson, Isak, Aznar, Susana, Gouras, Gunnar, Brudek, Tomasz, Hansen, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609689/ https://www.ncbi.nlm.nih.gov/pubmed/34334418 http://dx.doi.org/10.3233/JPD-202512 |
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