Efficacy of Istradefylline, an Adenosine A(2A) Receptor Antagonist, as Adjunctive Therapy to Levodopa in Parkinson’s Disease: A Pooled Analysis of 8 Phase 2b/3 Trials

BACKGROUND: Istradefylline is a selective adenosine A(2A) receptor antagonist for the treatment of patients with Parkinson’s disease (PD) experiencing OFF episodes while on levodopa/decarboxylase inhibitor. OBJECTIVE: This pooled analysis of eight randomized, placebo-controlled, double-blind phase 2...

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Detalles Bibliográficos
Autores principales: Hauser, Robert A., Hattori, Nobutaka, Fernandez, Hubert, Isaacson, Stuart H., Mochizuki, Hideki, Rascol, Olivier, Stocchi, Fabrizio, Li, June, Mori, Akihisa, Nakajima, Yu, Ristuccia, Robert, LeWitt, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609697/
https://www.ncbi.nlm.nih.gov/pubmed/34486986
http://dx.doi.org/10.3233/JPD-212672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609697/
https://www.ncbi.nlm.nih.gov/pubmed/34486986
http://dx.doi.org/10.3233/JPD-212672

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