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Cerebral Amyloid Angiopathy in a Mouse Model of Alzheimer’s Disease Associates with Upregulated Angiopoietin and Downregulated Hypoxia-Inducible Factor

BACKGROUND: Vascular pathology is a common feature in patients with advanced Alzheimer’s disease, with cerebral amyloid angiopathy (CAA) and microvascular changes commonly observed at autopsies and in genetic mouse models. However, despite a plethora of studies addressing the possible impact of CAA...

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Detalles Bibliográficos
Autores principales: Skaaraas, Gry H.E. Syverstad, Melbye, Christoffer, Puchades, Maja A., Leung, Doreen Siu Yi, Jacobsen, Øyvind, Rao, Shreyas B., Ottersen, Ole Petter, Leergaard, Trygve B., Torp, Reidun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609707/
https://www.ncbi.nlm.nih.gov/pubmed/34459401
http://dx.doi.org/10.3233/JAD-210571