A Summary of Phenotypes Observed in the In Vivo Rodent Alpha-Synuclein Preformed Fibril Model

The use of wildtype recombinant alpha-synuclein preformed fibrils (aSyn PFFs) to induce endogenous alpha-synuclein to form pathological phosphorylation and trigger neurodegeneration is a popular model for studying Parkinson’s disease (PD) biology and testing therapeutic strategies. The strengths of...

Descripción completa

Detalles Bibliográficos
Autor principal: Polinski, Nicole K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609716/
https://www.ncbi.nlm.nih.gov/pubmed/34486988
http://dx.doi.org/10.3233/JPD-212847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609716/
https://www.ncbi.nlm.nih.gov/pubmed/34486988
http://dx.doi.org/10.3233/JPD-212847

Ejemplares similares