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Molecular interactions in remdesivir-cyclodextrin systems

Remdesivir (REM) is the first antiviral drug (Veklury™) approved by the Food and Drug Administration for the therapy of COVID-19. Due to its poor water solubility, the preparation of Veklury™ requires a suitable solubilizing excipient at pH 2 conditions. For this purpose, the final formulation conta...

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Detalles Bibliográficos
Autores principales: Várnai, Bianka, Malanga, Milo, Sohajda, Tamás, Béni, Szabolcs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609759/
https://www.ncbi.nlm.nih.gov/pubmed/34856493
http://dx.doi.org/10.1016/j.jpba.2021.114482