GSA: an independent development algorithm for calling copy number and detecting homologous recombination deficiency (HRD) from target capture sequencing

BACKGROUND: The gain or loss of large chromosomal regions or even whole chromosomes is termed as genomic scarring and can be observed as copy number variations resulting from the failure of DNA damage repair. RESULTS: In this study, a new algorithm called genomic scar analysis (GSA) has developed an...

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Detalles Bibliográficos
Autores principales: Chen, Dongju, Shao, Minghui, Meng, Pei, Wang, Chunli, Li, Qi, Cai, Yuhang, Song, Chengcheng, Wang, Xi, Shi, Taiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609767/
https://www.ncbi.nlm.nih.gov/pubmed/34814825
http://dx.doi.org/10.1186/s12859-021-04487-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609767/
https://www.ncbi.nlm.nih.gov/pubmed/34814825
http://dx.doi.org/10.1186/s12859-021-04487-9

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