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Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression

BACKGROUND: UCA1 is frequently upregulated in a variety of cancers, including CRC, and it can play an oncogenic role by various mechanisms. However, how UCA1 is regulated in cancer is largely unknown. In this study, we aimed to determine whether RNA methylation at N6-methyladenosine (m6A) can impact...

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Detalles Bibliográficos
Autores principales: He, Rong-Zhang, Jiang, Jing, Hu, Xinglin, Lei, Ming, Li, Jia, Luo, Weihao, Duan, Lili, Hu, Zheng, Mo, Yin-Yuan, Luo, Di-Xian, Peng, Wan-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609784/
https://www.ncbi.nlm.nih.gov/pubmed/34809621
http://dx.doi.org/10.1186/s12935-021-02288-x