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microRNA-194 is increased in polycystic ovary syndrome granulosa cell and induce KGN cells apoptosis by direct targeting heparin-binding EGF-like growth factor

BACKGROUND: Polycystic ovary syndrome (PCOS) is an endocrine-related follicular developmental disorder that affects 50 %-70 % of reproductive-aged women diagnosed with ovulation-related infertility. Abnormal proliferation and apoptosis of granulosa cells (GCs) are thought to be the critical factors...

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Detalles Bibliográficos
Autores principales: Wu, Yi-xuan, Lin, Yan-shan, Li, Si-chen, Yao, Xi, Cheng, Mingwei, Zhu, Lin, Liu, Hai-ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609843/
https://www.ncbi.nlm.nih.gov/pubmed/34814928
http://dx.doi.org/10.1186/s12958-021-00850-w