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Assessment of Tau Pathology as Measured by (18)F-THK5317 and (18)F-Flortaucipir PET and Their Relation to Brain Atrophy and Cognition in Alzheimer’s Disease

BACKGROUND: In Alzheimer’s disease (AD), the abnormal aggregation of hyperphosphorylated tau leads to synaptic dysfunction and neurodegeneration. Recently developed tau PET imaging tracers are candidate biomarkers for diagnosis and staging of AD. OBJECTIVE: We aimed to investigate the discriminative...

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Detalles Bibliográficos
Autores principales: Colato, Elisa, Chiotis, Konstantinos, Ferreira, Daniel, Mazrina, Mariam S., Lemoine, Laetitia, Mohanty, Rosaleena, Westman, Eric, Nordberg, Agneta, Rodriguez-Vieitez, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609906/
https://www.ncbi.nlm.nih.gov/pubmed/34511502
http://dx.doi.org/10.3233/JAD-210614