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Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometry

Type 2 diabetes mellitus (T2D) is a chronic age-related disorder characterized by hyperglycemia due to the failure of pancreatic beta cells to compensate for increased insulin demand. Despite decades of research, the pathogenic mechanisms underlying T2D remain poorly defined. Here, we use imaging ma...

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Detalles Bibliográficos
Autores principales: Wu, Minghui, Lee, Michelle Y.Y., Bahl, Varun, Traum, Daniel, Schug, Jonathan, Kusmartseva, Irina, Atkinson, Mark A., Fan, Guanjie, Kaestner, Klaus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609965/
https://www.ncbi.nlm.nih.gov/pubmed/34731614
http://dx.doi.org/10.1016/j.celrep.2021.109919