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CRISPR-Cas12a-Based Detection of SARS-CoV-2 Harboring the E484K Mutation

[Image: see text] The novel respiratory virus SARS-CoV-2 is rapidly evolving across the world with the potential of increasing its transmission and the induced disease. Here, we applied the CRISPR-Cas12a system to detect, without the need of sequencing, SARS-CoV-2 genomes harboring the E484K mutatio...

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Detalles Bibliográficos
Autores principales: Marqués, María-Carmen, Ruiz, Raúl, Montagud-Martínez, Roser, Márquez-Costa, Rosa, Albert, Sandra, Domingo-Calap, Pilar, Rodrigo, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610009/
https://www.ncbi.nlm.nih.gov/pubmed/34783536
http://dx.doi.org/10.1021/acssynbio.1c00323