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Therapeutic combination silencing VEGF and SOX10 increases the antiangiogenic effect in the mouse melanoma model B16-F10 – in vitro and in vivo studies

INTRODUCTION: Gene therapy is an innovative form of treatment of genetic diseases, in which psiRNA molecules silencing specific genes are applied. AIM: The study evaluated the anti-tumour effect of psiRNA silencing preparations of the vascular endothelial growth factor (VEGF) and Sry-related HMG-Box...

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Detalles Bibliográficos
Autores principales: Bogusławska-Duch, Joanna, Ducher-Hanaka, Magdalena, Zajkowska, Agnieszka, Czajka, Milena, Małecki, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610042/
https://www.ncbi.nlm.nih.gov/pubmed/34849139
http://dx.doi.org/10.5114/ada.2021.110461