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Construction and external validation of a 5-gene random forest model to diagnose non-obstructive azoospermia based on the single-cell RNA sequencing of testicular tissue

Non-obstructive azoospermia (NOA) is among the most severe factors for male infertility, but our understandings of the latent biological mechanisms remain insufficient. The single-cell RNA sequencing (scRNA-seq) data of 432 testicular cells isolated from the patient with NOA was analyzed, and the ce...

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Detalles Bibliográficos
Autores principales: Zhou, Ranran, Lv, Xianyuan, Chen, Tianle, Chen, Qi, Tian, Hu, Yang, Cheng, Guo, Wenbin, Liu, Cundong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610122/
https://www.ncbi.nlm.nih.gov/pubmed/34738918
http://dx.doi.org/10.18632/aging.203675