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LncRNA OTUD6B-AS1 promotes paclitaxel resistance in triple negative breast cancer by regulation of miR-26a-5p/MTDH pathway-mediated autophagy and genomic instability

Genomic instability (GIN) is pivotal in regulating tumor drug resistance, which blocked the treatment of triple negative breast cancer (TNBC). Although recent studies implied that non-coding RNA (ncRNA)-mediated autophagy abolishment promoted tumorigenesis by up-regulation of GIN, autophagy was know...

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Detalles Bibliográficos
Autores principales: Li, Peng-Ping, Li, Rong-Guo, Huang, Yu-Qing, Lu, Jin-Pian, Zhang, Wei-Jun, Wang, Zhen-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610138/
https://www.ncbi.nlm.nih.gov/pubmed/34740994
http://dx.doi.org/10.18632/aging.203672