Cyclophosphamide abrogates the expansion of CD4(+)Foxp3(+) regulatory T cells and enhances the efficacy of bleomycin in the treatment of mouse B16-F10 melanomas

OBJECTIVE: Promotion of the proliferative expansion of CD4(+)Foxp3(+) regulatory T cells (Tregs) is one of the side effects that limits the use of bleomycin (BLM) in the treatment of tumors. In this study, we examined the hypothesis that cyclophosphamide (CY), a chemotherapeutic agent with the capac...

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Detalles Bibliográficos
Autores principales: Li, Ping, Chen, Fengyang, Zheng, Jingbin, Yang, Yang, Li, Yuan, Wang, Yifei, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610150/
https://www.ncbi.nlm.nih.gov/pubmed/34378880
http://dx.doi.org/10.20892/j.issn.2095-3941.2021.0027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610150/
https://www.ncbi.nlm.nih.gov/pubmed/34378880
http://dx.doi.org/10.20892/j.issn.2095-3941.2021.0027

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