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Residue substitution enhances the immunogenicity of neoepitopes from gastric cancers

OBJECTIVE: Neoantigens arising from gene mutations in tumors can induce specific immune responses, and neoantigen-based immunotherapies have been tested in clinical trials. Here, we characterized the efficacy of altered neoepitopes in improving immunogenicity against gastric cancer. METHODS: Raw dat...

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Detalles Bibliográficos
Autores principales: Yu, Huahui, Li, Jieyu, Yuan, Yuan, Chen, Yu, Hong, Jingwen, Ye, Chunmei, Lin, Wansong, Chen, Huijing, Guo, Zengqing, Li, Bo, Ye, Yunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610152/
https://www.ncbi.nlm.nih.gov/pubmed/35959968
http://dx.doi.org/10.20892/j.issn.2095-3941.2021.0022