Analgesic effects of Phα1β toxin: a review of mechanisms of action involving pain pathways

Phα1β is a neurotoxin purified from spider venom that acts as a high-voltage-activated (HVA) calcium channel blocker. This spider peptide has shown a high selectivity for N-type HVA calcium channels (NVACC) and an analgesic effect in several animal models of pain. Its activity was associated with a...

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Detalles Bibliográficos
Autores principales: da Silva, Juliana Figueira, Binda, Nancy Scardua, Pereira, Elizete Maria Rita, de Lavor, Mário Sérgio Lima, Vieira, Luciene Bruno, de Souza, Alessandra Hubner, Rigo, Flávia Karine, Ferrer, Hèlia Tenza, de Castro, Célio José, Ferreira, Juliano, Gomez, Marcus Vinicius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610172/
https://www.ncbi.nlm.nih.gov/pubmed/34868281
http://dx.doi.org/10.1590/1678-9199-JVATITD-2021-0001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610172/
https://www.ncbi.nlm.nih.gov/pubmed/34868281
http://dx.doi.org/10.1590/1678-9199-JVATITD-2021-0001

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