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Edaravone Improves the Post-traumatic Brain Injury Dysfunction in Learning and Memory by Modulating Nrf2/ARE Signal Pathway

OBJECTIVES: To investigate the molecular mechanism of edaravone (EDA) in improving the post-traumatic brain injury (TBI) dysfunction in learning and memory. METHODS: In vitro and in vivo TBI models were established using hydrogen peroxide (H(2)O(2)) treatment for hippocampal nerve stem cells (NSCs)...

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Detalles Bibliográficos
Autores principales: Li, Xiushan, Yu, Jing, Ma, Dongzhou, Weng, Xuehui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Medicina / USP 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610218/
https://www.ncbi.nlm.nih.gov/pubmed/34878029
http://dx.doi.org/10.6061/clinics/2021/e3131